At Vectron Biosolutions, we have an industry-leading technology platform for production of proteins in bacteria, which overcomes and solves technical challenges frequently observed with conventional systems. Through Vectron's proprietary suite of next-generation expression tools, we can develop a tailored bacterial strain and upstream production process that produces your protein at higher titers (up to 60 g/L) and at higher quality (soluble, biologically active) leading to lowered cost of goods (up to 80%) and increased profitability.
Our comprehensive suite of services is tailored to optimize every stage of microbial protein production:
Enzyme Evolution and Screening: Evaluation of evolved enzyme activity and characterization of new and improved enzyme variants.
Strain Development and Screening: Establishment and identification of optimized recombinant protein-producing strains.
Fermentation: Seamless scale-up to industrially relevant high cell density cultivation conditions, progressing from bench to pilot scale.
Upstream Process Characterization: In-depth process analysis of metabolites, nutrients, online data, substrate/medium optimization, and by-product identification.
Purification/Protein Quality Assessment: Isolation of the protein of interest at bench- and prep-scale, including the evaluation of endotoxin levels, host DNA, metals, etc.
Protein Analysis: Rigorous evaluation of product quality, encompassing intact mass, glycan and disulfide bond profiling.
In-vitro characterization includes activity, binding affinity, anti-microbial, anti-fungal, and antiviral activity, along with determination of titer.
